Bisphenol-A based benzoxazine monomer (BA-m) and its oligomer are applied as an ionophore to study by Pedersen's technique, the ion interaction with alkali and alkaline earth ions. Ion extraction efficiencies are significant when the solubility parameter of the organic phase is close to that of BA-m or the chi-parameter is 0.34. Ionophore concentration controls the amount of metal ion extraction. Both BA-m and its oligomer show high entrapment efficiency over 70% extraction, for all types of ions.