In the present study the results of traditional methods for characterizing 25 lignite samples, representing a continuous sequence of the Drama deposit, Northern Greece, are presented. The moisture, the volatile matter, and the ash contents are high, while the sulfur content remains at low levels. Rock-Eval analysis was performed on the same samples. The T-max values obtained do not correlate with coal type and rank and are higher than those expected for lignites. The reflectivity values are lower than 0.2%. In values < 0.5% R-m and > 1.5% R-m, T-max does not correlate with R-m. It is also noticed that the difference in hydrogen contents is not related to the T-max values as would be expected. The concentrations of U-238 U-235, Ra-226, Pb-210 Ra-228, Th-228, and K-40, determined in samples D2 and D5, are similar to those reported in the literature for Greek lignites. The concentrations of uranium-series isotopes are among the higher for lignites worldwide.