A tectono-sedimentary sequence is proposed from field and subsurface data, which illustrates the evolution of the Morondava basin (Western Madagascan margin) during the Jurassic. The main events are evidenced as follows: Pre-Toarcian faulting of the Upper Karroo series, burying and sealing of Karroo tilted blocks and development of a levelling surface by the end of the Liassic, initiation of marine influence during the Toarcian, development of prograding carbonate or elastic platforms (Dogger), initiation and development of a basinal environment from the Callovian to Late Jurassic/Neocomian, Late Jurassic/Eocretaceous faulting resulting from the reactivation of the Karroo rift fault system; uplift and erosional episode, mafic intrusions from the Middle Jurassic to Albo-Cenomanian, deposition of Aibo-Cenomanian clastics which rest unconformably on the eroded and faulted underlying series. An attempt is made to correlate these events with the evolution of the Mozambique Channel and adjacent oceanic basins.