The southern Gulf of Suez in Egypt is located at the junction of the African and Arabian plates, and has excellent hydrocarbon potential. The stratigraphic units in the area are grouped into two main megasequences, the pre-rift (PreOligocene) and the syn-rift (Oligocene-Recent) lithostratigraphic units. Gravity, magnetic, seismic and well data were used to delineate outlines of several narrowly elongated northwest-trending depositional troughs, separated by structural ridges. Several pre-rift and syn-rift rich source units occur and are mature enough in the deep troughs to generate hydrocarbons. A geochemical study of source rocks and oil samples showed two groups of oil: 1. Gulf of Suez oils from pre-rift sediments; and 2. southern Gulf of Suez oils from Middle Miocene carbonates. The reservoirs are also classified into: 1. pre- rift reservoirs, such as fractured and weathered Precambrian basement, Nubia sandstone, Cretaceous sandstone and fractured Eocene limestone; and 2. syn-rift reservoirs such as Lower and Middle Miocene carbonates and sandstones. Most oil fields in the region have multiple, producing reservoirs. The Miocene Evaporite Group forms the primary seal for most of the reservoirs, and the shales and dense carbonates of both the pre-rift and syn-rift sections form secondary seals. Trap types include structural, stratigraphic and combination traps. The southern Gulf of Suez, which shares more than one-third of the whole Gulf of Suez reserves, remains high in hydrocarbon potential with many untested plays.