This paper is about the sensitivity of detection of multiple solutions to the structures or parameters incorporated in the equation system that represents a distillation column. The performance of different column simulation models, generally carried out in commercial simulators, is tested to detect multiplicity. The influence of the physicochemical estimating methods and the adopted numeric strategies to solve distillation problems is considered. Important behavioral differences have been found according to the model, the calculation method and the thermodynamic properties package used. Besides, the starting point is very important in the search of the hysteresis loop.