A folded-sheet mesoporous material (FSM-16) was prepared, and its adsorption selectivity for several organic compounds (p-nitrophenol, toluene, n-heptane, benzene, cyclohexane, and o-dichlorobenzene) was studied. The adsorbed amounts of these compounds were measured by batch operation in liquid phase. The p-nitrophenol in aqueous solution was hardly adsorbed into FSM16, but toluene (in n-heptane solvent) and benzene (in n-heptane solvent or cyclohexane solvent) were adsorbed into FSM-16. The adsorption capacity of these preferentially adsorbed components into FSM-16 was higher than that into commercial adsorbents (13X zeolite and silica gel) because of the higher pore volume of FSM-16. The results obtained by the column method showed that FSM-16 column was useful for separating organic compounds.