A numerical study is performed to demonstrate the influence of a nonuniform fluid distribution on the regeneration behavior of ceramic fiber coil filters of industrial size. A detailed knowledge of the soot distribution inside the filter proves to be a prerequisite for predicting the regeneration behavior adequately. Therefore, a two-dimensional mathematical model is developed which is able to simulate the filtration as well as the regeneration behavior. For a given soot distribution the inlet mass flow is identified as the important factor determining the overall regeneration behavior. Hints are given to ensure a controlled regeneration in view of a long lifetime of such filters.