Journal of Bioscience and Bioengineering, Vol.89, No.3, 271-273, 2000
Dibutyl phthalate, an alpha-glucosidase inhibitor from Streptomyces melanosporofaciens
Dibutyl phthalate was found to inhibit alpha-glucosidase, alpha- and beta-mannosidases and beta-glucosidase, in that order of inhibition strength. Dibutyl phthalate was shown to be a reversible, slow-binding, noncompetitive inhibitor of yeast alpha-glucosidase with a K-i value of 3.9 mu M.