Measures of mixture homogeneity and their links with mixing time measurements were discussed, The statistical foundations of homogeneity measures for different scales of scrutiny were presented, followed by the differential mixing model application to defining conditions of physical similarity for macromixing. Selected variable effects on mixing time were studied by means of the CFD analysis. The conclusions drawn from this study can help understand importance of some process parameters. Reasons for a broader discussion on standard experimental procedures were also specified.