The 15 most widespread adsorption isotherm equations are applied for describing recently published paracetamol adsorption data from aqueous solutions (pH 7). Twelve adsorption isotherms, measured at 300, 310, and 320 K, on the series of chemically modified carbons D43/1 (Carbo-Tech, Essen, Germany) differing in surface properties (from basic to strongly acidic) but possessing almost the same porosity, are analyzed. The results of fitting theoretical models to experimental data are arranged according to a decrease in the average value of the determination coefficient. From the models studied the best fit is obtained for Weber-Vliet, Dubinin-Astakhov, and the model published by Jossens. The most important conclusion is that at the lowest temperature studied, where the effect of carbon surface composition on adsorption properties is the most strongly marked, the value of paracetamol maximal adsorption decreases as the amount of surface basic groups and carbonyls increases.