The catalytic properties of bulk V2O5, CuO-Cr2O3 mixed oxide, and these oxides supported on gamma-Al2O3, i.e. V2O5/gamma-Al2O3, Cu-Cr-O/gamma-Al2O3 were studied in total oxidation of nitromethane, ethylenediamine (EDA) and N,N-dimethylformamide (DNIF) in air. The catalytic behaviour of studied catalysts was compared with an industrial catalyst. The CO2, CO, H2O, N-2, N2O, NO and NO2 were found as the products of reaction. The composition of the reaction products strongly depended on the type of the catalyst, It was found that Cu-Cr-O/gamma-AlO3 catalyst oxidized the organic part of studied compounds to CO2 and H2O but a lot of NOx was observed in the reaction products. V2O5/gamma-Al2O3 had a lower ability for total oxidation of organic compounds to CO2. The CO was observed in products of DMF and EDA oxidation over V2O5/gamma-Al2O3 but selectivity to N-2 was near 100% in all cases. IR spectra of adsorbed compounds showed that differences in catalytic properties among studied systems were probably connected with a specific adsorption of a given organic compound on the surface of the catalysts.