The analysis of the effective radial thermal conductivity and the film heat transfer coefficient were carried out in a fixed bed. The temperature profiles were described by two-dimensional pseudo-homogeneous model. The thermal parameters were estimated using a sequential experimental design technique. The minimum volume criterion was used to design the next point for temperature measurement in the bed. The utilization of T = T-0 (constant) as the boundary condition at the bed inlet resulted in an axial variation of thermal parameters, which was the factor responsible for the inadequacy of the model in fitting experimental data of different bed heights simultaneously. Using T= T(r) as the boundary condition makes the thermal parameters independent of the axial position and the model statiscally adequate to describe the axial and radial temperature profiles throughout the bed.