The solubility of Ls-36 and Ls-45 surfactants in supercritical (SC) CO2 and the phase behavior of CO2/water/surfactant systems were studied at different temperatures and pressures. The results showed that the solubility of the surfactants in SC CO2 is high although they are non-fluorous and non-silicone containing surfactants. Moreover, the loading water of the 0.02 M Ls-36/SC CO2 and Ls-45/SC CO2 systems, which was characterized by the molar ratio of water to surfactant, W-0(corr), was up to 7.9. The results of this work provide useful information for designing other low-cost CO2-philic non-fluorous and non-silicone containing surfactants.