The degradation of organic compounds in water is the subject of a great number of fundamental and applied investigations. The aquasonolysis of organic can be used as an advanced technology for remediation of contaminated water. The process is based on phenomena of acoustic cavitation. The dominant reactions of volatile compounds are both cavitative high-temperature gasphase reactions and thermal-oxidative decays in bubbles. Non-volatile compounds are mainly destroyed by OH-radicals in the aqueous solution (sonolytic cleaving of water). This paper gives a state-of-the-art overview of ultrasound as a tool for the degradation of pollutants in wastewater.