Propionic acid-water is one of the minimum boiling point azeotropic binary mixtures. Alteration of the vapor-liquid equilibrium (VLE) by addition of inorganic salts is of interest, since it allows bypassing the azeotropic point due to salt-in and salt-out effects. The effect of NaCl, NH4Cl, CaCl2, and AlCl3 at salt concentrations of I m and the effect of NaCl molality (0.5-3 m) on the VLE of the binary propionic acid-water mixture has been experimentally investigated at 60 degreesC using the headspace gas chromatography (HSGC) technique. The alteration in the VLE of the system was salt type and salt concentration dependent. Salting out of the propionic acid was observed when salts were added and was most obvious in the case of AlCl3 salt. The salt effect parameter, determined from the Futter's equation was a function of the liquid concentration.