Heat transfer was studied for the case of autowave transition from metastable to stable boiling regimes. The boiling curves classification was proposed in dependence on the direction of the vectorial parameters, such as temperature gradient, flow and temperature wave velocity. According to the proposed hypothesis, considerable changes in heat transfer relationships in the regions affected by temperature waves can be explained by local non-equilibrium near-to-wall layers. The experiments were conducted to study heat transfer in case of autowave change of boiling conditions in tubes in the pressure range from 3 to 10 MPa and in the broad range of steam quality and mass velocity. It was demonstrated that the change of boiling regimes in tubes in the form an autowave could be observed if the steam quality was less than its boundary value. The paper also discusses possible application of the obtained data for simulation of abnormal processes in the reactor core.