Several hybrid systems, which are developed now, namely NF-MSF, NF-RO-MSF, NF-RO-MD and others offer promising performance. An integrated system for complete usage of components in seawater is also being considered. In all the aforementioned systems NF as water pre-treatment method is applied and a considerable decrease in scale forming components is achieved. Higher recovery may be then reached when desalting in comparison to traditionally treated water. Very compact NF membranes are applied which results in a very high rejection of divalent ions and relatively hi-h rejection of sodium chloride. A simultaneous decrease of NaCl concentration in NF process is then obtained which causes an increase in the RO recovery since the osmotic pressure value of NF permeate is diminished. If NF-MSF (or NF followed by any thermal method) system is considered a NaCl concentration decrease in the pretreatment is however not essential for the NF step. The salt concentration influence on thermal method performance is very weak in comparison to RO. Furthermore the highly concentrated MSF brine might be used as a possible by-product, e.g. for obtaining salt. A dual-purpose desalination-salt production system may be then suggested. Two arrangements are presented, namely: UF-NF-MSF-crystallisation and UF-NF-RO-MSF-crystallisation systems. The high rate of water recovery is accompanied by salt obtainment in these systems. If $30/ton of salt is assumed the water cost is equal to $0.71/m(3) in UF-NF-MSF-crystallisation system and $0.43/m(3) in UF-NF-RO-MSF-crystallisation system. The above data demonstrate that these water costs are competitive compared to those of potable water produced in thermal or RO seawater plants.