Fuzzy modeling and control based on the fuzzy sets theory have been used in the biotechnology field for the last two decades. Recent studies on fuzzy modeling and control of various biological processes are reviewed. In addition, five applications of fuzzy control to industrial biological processes are summarized, compared and discussed in terms of the system features, control purpose, input and output variables, development of fuzzy rules and effectiveness. Fuzzy modeling and control are regarded as promising methods for automating the bioprocesses in which experienced operators play significant roles in their successful operation.