화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Korean Journal of Chemical Engineering, Vol.20, No.5, 791-798, September, 2003
DOI10.1007/BF02697278  Export Citation
Beyond Process Design: The Emergence of a Process Development Focus
Ka Ming Ng†, and Christianto Wibowo1
  • Department of Chemical Engineering, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
  • 1Clear Water Bay Technology, Inc., 20311 Valley Blvd., Suite C, Walnut, CA 91789, USA
E-mail:
This article suggests that process development, consisting of process research and innovation, pilot plant, technology transfer and manufacturing, will play a key role in the evolution of chemical engineering as a profession. By integrating science, engineering and management with a multiscale approach, process development helps break down artificial barriers, leading to performance optimization from an enterprise-wide perspective.
Keywords:Process Synthesis;Process Design;Process Development;Technology Transfer;Munufacturing
  1. Arora A, Landau R, Rosenberg N, "Chemicals and Long-Term Economic Growth," John Wiley & Sons, New York (1998)
  2. Barton KP, Irdam EA, Seymour CB, Behling JR, "Partnering for Success: ACE Teams in Drug Process Development," AIChE Annual Meeting, Los Angeles, Paper 274c (2000)
  3. Basu PK, Mack RA, Vinson JM, Chem. Eng. Prog., 95(8), 82 (1999)
  4. Basu PK, Chem. Eng. Prog., 94(9), 75 (1998)
  5. Berry DA, Dye SR, Ng KM, AIChE J., 43(1), 91 (1997) 
  6. David A, Ng KM, AIChE J., 42(8), 2162 (1996) 
  7. Biegler LT, Grossmann IE, Westerberg AW, "Systematic Methods of Chemical Process Design," Prentice Hall, Upper Saddle River, NJ (1997)
  8. Bisio A, Kabel RL, "Scaleup of Chemical Processes: Conversion from Laboratory Scale Tests to Successful Commercial Size Design," Wiley, New York, NY (1985)
  9. Cesar MAB, Ng KM, Ind. Eng. Chem. Res., 38(3), 823 (1999) 
  10. Chang WC, Ng KM, AIChE J., 44(10), 2240 (1998) 
  11. Cherney S, Rappaport J, "International Technology Transfer," AIChE Spring Meeting, Houston, Session 101 (2001)
  12. Davis WP, "Transfer of Pharmaceutical Processes to Overseas Contract Manufacturers," AIChE Spring Meeting, Houston, Paper 101a (2001)
  13. Doherty MF, Malone MF, "Conceptual Design of Distillation Systems," McGraw Hill, New York (2001)
  14. Douglas JM, "Conceptual Design of Chemical Processes," McGraw-Hill, New York (1988)
  15. Dye SR, Ng KM, AIChE J., 41(6), 1456 (1995) 
  16. Dye SR, Ng KM, AIChE J., 41(11), 2427 (1995) 
  17. Economist, Nanoelectronics, May 10, p. 67 (2003)
  18. Grossmann IE, Westerberg AW, AIChE J., 46(9), 1700 (2000) 
  19. Hoyle W, "Pilot Plants and Scale-up of Chemical Processes," I and II, The Royal Society of Chemistry, Cambridge, UK (1997)
  20. Kelkar VV, Ng KM, AIChE J., 48(7), 1498 (2002) 
  21. Kelkar VV, Ng KM, AIChE J., 44(7), 1563 (1998) 
  22. Kelkar VV, Ng KM, AIChE J., 46(2), 389 (2000) 
  23. Kim CJ, "Supply Chain Management in Process Industry," Keynote Presentation at PSE Asia, Taipei (2002)
  24. Kind M, Chem. Eng. Process., 38(4-6), 405 (1999) 
  25. Kwok KS, Chan HC, Chan CK, Ng KM, "Experimental Determination of Solid Liquid Equilibrium Phase Diagrams," Manuscript in Preparation (2003)
  26. Landau R, Chem. Eng. Prog., 93(1), 52 (1997)
  27. Lerou JJ, Ng KM, Chem. Eng. Sci., 51(10), 1595 (1996) 
  28. Mansfield S, "Engineering Design for Process Facilities," McGraw-Hill, New York, NY (1993)
  29. McConville FX, "The Pilot Plant Real Book," FXM Engineering and Design, Worcester, MA (2002)
  30. Merrow EW, Chem. Eng. Prog., 81(5), 14 (1985)
  31. Moggridge GD, Cussler EL, Chem. Eng. Res. Des., 78(1), 5 (2000) 
  32. Ng KM, "A Multiscale-Multifaceted Approach to Process Synthesis and Development," ESCAPE11, Ed. R. Gani and S.B. Jorgensen, 41, Elsevier (2001)
  33. Ng KM, Powder Technol., 126(3), 205 (2002) 
  34. Ng KM, "MOPSD: A Framework Linking Business Decision-Making to Product and Process Design," Paper Presented at PSE, Kunming, China (2003)
  35. Palluzi RP, "Pilot Plant Design, Construction, and Operation," McGraw-Hill, New York (1992)
  36. Rajagopal S, Ng KM, Douglas JM, Comput. Chem. Eng., 16, 675 (1992) 
  37. Rajagopal S, Ng KM, Douglas JM, AIChE J., 37, 437 (1991) 
  38. Reklaitis GV, "Preparation of Chemical Engineers for Manufacturing Leadership in the 21st Century," Phillips Petroleum Company Lecture Series, Oklahoma State University, Stillwater, OK (2000)
  39. Saban M, Dale B, "Knowledge-Sharing for Technology Transfer in the Chemical Industry: A Case Study," AIChE Spring Meeting, Houston, Paper 101d (2001)
  40. Samant KD, Berry DA, Ng KM, AIChE J., 46(12), 2435 (2000) 
  41. Samant KD, Ng KM, AIChE J., 44(10), 2212 (1998) 
  42. Samant KD, Ng KM, AIChE J., 45(11), 2371 (1999) 
  43. Samant KD, Ng KM, AIChE J., 47(4), 861 (2001) 
  44. Sarafinas A, Roemmele RC, Eagleton JC, "An Integrated Approach to Agricultural Intermediate Process Development," AIChE Annual Meeting, Los Angeles, Paper 274b (2000)
  45. Schroer JW, Ng KM, Ind. Eng. Chem. Res., 42(10), 2230 (2003) 
  46. Schroer JW, Wibowo C, Ng KM, AIChE J., 47(2), 369 (2001) 
  47. Scriven LE, Adv. Chem. Eng., 16, 3 (1991)
  48. Seider WD, Seader JD, Lewin DR, "Process Design Principles," Wiley, New York, NY (1999)
  49. Singh DJ, Samant KD, Ng KM, AIChE J., 48(9), 1991 (2002) 
  50. Snodgrass JT, Dalgarno DC, Canning K, "Analytical Methods Transfer for Early Stage Pharmaceutical Development," AIChE Spring Meeting, New Orleans, Paper 148g (2003)
  51. Tanguy D, Marchal P, Chem. Eng. Res. Des., 74(7), 715 (1996)
  52. Tirronen E, Salmi T, Chem. Eng. J., 91(2-3), 103 (2003) 
  53. Turton R, Bailie RC, Whiting WB, Shaeiwitz JA, "Analysis, Synthesis, and Design of Chemical Processes," Prentice Hall, Upper Saddle River, NJ (1998)
  54. Ung S, Doherty MF, Ind. Eng. Chem. Res., 34(8), 2555 (1995) 
  55. Wibowo C, Chang WC, Ng KM, AIChE J., 47(11), 2474 (2001) 
  56. Wibowo C, Ng KM, AIChE J., 47(1), 107 (2001) 
  57. Wibowo C, Ng KM, AIChE J., 45(8), 1629 (1999) 
  58. Wibowo C, Ng KM, AIChE J., 46(7), 1400 (2000) 
  59. Wibowo C, Ng KM, AIChE J., 48(5), 991 (2002) 
  60. Wibowo C, Ng KA, AIChE J., 48(6), 1212 (2002) 
  61. Wibowo C, Ng KM, Ind. Eng. Chem. Res., 41(16), 3839 (2002) 
  62. Wibowo C, O'young L, Ng KM, "Workflow Management in Chemical Process Development," manuscript in Preparation (2003)
  63. Wibowo C, Samant KD, Ng KM, AIChE J., 48(10), 2179 (2002) 
  64. Williams F, Gibson DV, "Technology Transfer, A Communication Perspective," Sage Publications, Newbury Park, CA (1990)
  65. Wintermantel K, Chem. Eng. Res. Des., 77(3), 175 (1999) 
  66. Woods DR, "Process Design and Engineering Practice," Prentice Hall, Upper Saddle River, NJ (1995)
  67. Zukoski C, Armstrong R, Rousseau R, "Discipline at a Crossroads," a Chemical Engineering Leadership Workshop, Houston (2002)