A series of random copolymers, poly(perfluorooctylethylene methacrylate)-poly(propylene glycol) methacrylate, were synthesized as dispersants for dispersion polymerizations of methyl methacrylate in CO2. The results show that the composition of copolymeric dispersants has a dramatic effect on the polymerization yield and on the morphology of the resulting poly(methyl methacrylate) particles. The effect of varying the dispersant concentration, monomer concentration, and the initial medium pressure on the resultant polymerization was also investigated.