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Journal of Industrial and Engineering Chemistry, Vol.9, No.5, 473-480, September, 2003
HPLC Separation of Peptides from Human Blood
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The current study reviews previous reports on High Performance Liquid Chromatography (HPLC) related to biological liquids that contain biologically active peptides. Since various types of HPLC can be used to study peptides in biological liquids, including human blood, the medical, biological, and criminological applications of HPLC are investigated. Furthermore, as chromatography can separate preparative secretions and identify different peptides in human blood, the application of different HPLC methods for examining the peptides in human blood is also discussed. Finally, the influence of various factors on the mechanisms, characteristics, and results of peptide separation is considered. The outcomes of HPLC studies on the peptides in human blood can be employed in other biochemical studies, used to form peptidograms, and clinically applied for diagnosis during treatment.
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