Temperature and pH-responsive hydrogels were prepared with the combination of various monomers such as N-isopropylacrylamide (NIPAAm), acrylamide(AAm), n-butoxymethylacrylamide (nBMA), poly(ethylene glycol) methyl ether methacrylate (PEG), and acrylic acid (AAc). 2,4-Dichlorophenoxyacetic acid was chosen as the herbicide loaded into hydrogel. Volume transition, swelling behavior and release property were studied for these hydrogels. Poly(NIPAAm) hydrogel showed the sensitivity to the thermal stimuli at around 30 ℃ with a large volume change. nBMA was incorporated in a proper composition for the preparation of thermal stimuli-sensitive hydrogels which have AAc as one of their components showed very different behavior depending on the pH. Volume transition temperature, degree of swelling, and release rate were varied significantly depending on the content of comonomer, graft, and crosslinker.