The enthalpies of solution of the n-alcohols, ethanol to hexanol, have been measured in aqueous mixtures of formamide, N,N-dimethylacetamide and N-methylpyrrolidinone. The average enthalpy of transfer of the -CH2- moiety, Delta(t)H(theta)(CH2) from the organic solvents to the mixtures and to pure water are determined from the differences between the enthalpies of transfer of the alcohols. The Delta(t)H(theta)(CH2) values pass through maxima in the highly aqueous composition region, with the height of the maximum increasing linearly with the area of the hydrophobic surfaces of the cosolvent. These results are compared to similar data for the aqueous alcohol solvent systems where the maximum in Delta(t)H(theta)(CH2). is also sensibly linear in the area of the cosolvent hydrophobic surfaces but increases more rapidly with increasing hydrophobic area.