Effect of Phenol on β-Carotene Content in Total Carotenoids Production in Cultivation of Rhodotorula glutinis

Bong Kyun Kim; Pyoung Kyu Park; Hee Jeong Chae; Eui Yong Kim

Korean Journal of Chemical Engineering, Vol.21, No.3, 689-692, May, 2004

DOI10.1007/BF02705506 Export Citation

Effect of Phenol on β-Carotene Content in Total Carotenoids Production in Cultivation of Rhodotorula glutinis

Bong Kyun Kim, Pyoung Kyu Park¹, Hee Jeong Chae², and Eui Yong Kim^{1, †}

R&D Center, SEMO Co. Ltd., Incheon 558-10, Korea
¹Department of Chemical Engineering, University of Seoul, Seoul 130-743, Korea
²Department of Food and Biotechnology, and Department of Innovative Industrial Technology, Hoseo University, Asan 336-795, Korea

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The composition of carotenoids produced by R. glutinis was observed to be dependent upon the addition of phenol into medium. A stimulatory effect of phenol on β-carotene of Rhodotorula glutins K-501 grown on glucose was investigated. Carotenoids produced by Rhodotorula glutinis K-501 were identified to torularhodin, torulene and β-carotene, whose composition was 79.5%, 6.4% and 14.1%, respectively. The β-carotene content increased up to 35% when phenol was added to culture media at 500 ppm. The ratio of torularhodin decreased with increasing phenol concentration, while torulene content was almost constant.

Keywords:Phenol;β-Carotene;Carotenogenic Ratio;Rhodotorula glutinis

[References]

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Bhosale P, Gadre RV, Biosource Technol., 76, 53 (2001)
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[Referenced By]

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[1] An GH, Cho MH, Jang BG, J. Biosci. Bioeng., 92, 121 (2001)

[2] An GH, Schuman DB, Johnson EA, Appl. Environ. Microbiol., 55, 116 (1989)

[3] Bhosale P, Gadre RV, Biosource Technol., 76, 53 (2001)

[4] Boyer RF, "Modern Experimental Biochemistry," The Benjamin/Cummings Publishing Company, San Francisco, USA (1993)

[5] Costa I, Martelli HL, DaSilva IM, Pomeroy D, Biotechnol. Lett., 9, 373 (1987)

[6] Edge R, McGarvey DJ, Truscott TG, Photochem. Photobiol., 41, 189 (1997)

[7] Feist CF, Heheman GD, J. Bacteriol., 100, 869 (1969)

[8] Frengova GI, Simova ED, Beshkova DM, Biotechnol. Lett., 17(9), 1001 (1995)

[9] Gerster H, Inter. J. Vit. Nutr. Res., 63, 93 (1992)

[10] Girard P, Falconnier B, Bricout J, Vladescu B, Appl. Microbiol. Biotechnol., 41(2), 183 (1994)

[11] Katayama-Hirayama K, Tobita S, Hirayama K, J. Gen. Appl. Microbiol., 37, 379 (1991)

[12] Katayama-Hirayama K, Tobita S, Hirayama K, J. Gen. Appl. Microbiol., 37, 147 (1991)

[13] Katayama-Hirayama K, Tobita S, Hirayama K, Water Sci. Technol., 30, 59 (1994)

[14] Kim EY, Park PK, Chae HJ, Korean J. Biotechnol. Bioeng., 13, 58 (1997)

[15] Krebs HA, Wiggins D, Stubbs M, Biochem. J., 214, 657 (1983)

[16] Meyer PS, DuPreez JC, System. Appl. Microbiol., 17, 24 (1994)

[17] Miller GL, Anal. Chem., 31, 426 (1959)

[18] Nam HS, Cho SY, Rhee JS, J. Chromatogr., 448, 445 (1988)

[19] Nakayama T, Mackinney G, Phaff HJ, J. Microbiol. Serol., 20, 217 (1954)

[20] Nelis HJ, DeLeenheer AP, J. Appl. Bacteriol., 70, 181 (1991)

[21] Nesaretnam K, Lim EJ, Reimann K, Lai LC, Toxicology, 151, 117 (2000)

[22] Parajo JC, Santos V, Vazquez M, Process Biochem., 33(2), 181 (1998)

[23] Park HJ, Chung TS, Korean J. Chem. Eng., 20(4), 731 (2003)

[24] Polulyakh OV, Podoprigora OI, Eliseev SA, Ershov YV, Bykhovsk VY, Dmitrovsk AA, Prikladnaya Biokhimiya Mikrobiologiy, 27, 541 (1991)

[25] Sies H, Stahl W, Mol. Aspects Med., 24, 345 (1987)

[26] Schroeder WA, Johnson EA, J. Gen. Microbiol., 139, 907 (1993)

[27] Schroeder WA, Johnson EA, J. Ind. Microbiol., 14, 502 (1995)

[28] Simpson KL, Nakayama TOM, Chichester CO, J. Bact., 88, 1688 (1964)

[29] Walker N, Soil Biol. Biochem., 5, 525 (1973)

[30] Xiaoli Y, Huixiang S, Dahui W, Korean J. Chem. Eng., 20(4), 679 (2003)

[31] Young AJ, Lowe GM, Vlismas K, Mol. Aspects Med., 24, 363 (2003)

[32] Young A, Britton G, "Carotenoids in Photosynthesis," Chapman & Hall, London, UK (1993)