Although numerous coatings have been synthesized from guayule rubber derivatives, there have been no studies detailing the weatherability of such coatings. We report herein the results of accelerated weathering tests on powder coatings synthesized from epoxidized guayule rubber (EGR) and hydroxy-fluoroester pendent guayule rubber (FGR) derivatives. Our studies indicate that EGR and FGR powder coatings exposed to alternating cycles of fluorescent UVA light and water condensation for 400 h exhibit reduced yellowing and a high degree of gloss retention. (C) 2004 Wiley Periodicals, Inc.