Applied Biochemistry and Biotechnology, Vol.113-16, 381-388, 2004
Gibberellic acid production by free and immobilized cells in different culture systems
Gibberellic acid production was studied in different fermentation systems. Free and immobilized cells of Gibberella fujikuroi cultures in shake-flask, stirred and fixed-bed reactors were evaluated for the production of gibberellic acid (GA(3)). Gibberellic acid production with free cells cultured in a stirred reactor reached 0.206 g/L and a yield of 0.078 g of GA(3)/g biomass.
Keywords:cell immobilization;gibberellic acid;Gibberella fujikuroi;shake flasks;free cells;immobilized cells