The aim of this study was to verify the feasibility of drying pharmaceutical microcapsules in a spouted bed with the aid of inert particles. The morphological character and total recovery of the drug model, indomethacin, were compared for spray and spouted bed dried microcapsules. Clusters formed by microcapsules coalescence in the spouted bed showed to have their size dependent on bed height. The total recoveries for three different bed heights were 53.18%, 60.76%, 70.70%, as compared to 95.65% for the spray drying process. The results showed that spouted beds are promising for the preparation of slow-release drug systems.