CdS/dendrimer nanocomposites can be synthesized from methanolic Cd2+ and S2- with amine-terminated polyamidoamine dendrimers of generation 8 (G8NH(2)) as stabilizers. By controlling the preparation conditions, nanoparticles with diameters less than or equal to2 nm can be obtained with a narrow size distribution. They show blue photoluminescence at similar to450 nm. We studied the effects of various additives on the photoluminescence and elucidated its mechanism. Stable aggregates of two to three G8NH(2) molecules with several US nanoparticles form; the particles are located at the surface of the G8NH(2) molecules. The adsorption of the CdS/G8NH(2) nanocomposites on flat substrate surfaces is determined by the substrate chemistry. The hydrophilic nature of G8NH(2) results in weak affinity to graphite but strong affinity to hydroxy-terminated substrates such as mica, oxidized silicon wafers, and carboxylate-terminated monolayers. Patterning of nanocomposites on these hydrophilic substrates is achieved by the microcontact printing method. We propose to use only one molecule, a large dendrimer, to control the nanoparticle formation and also the immobilization of the synthesized nanoparticle/dendrimer composites.