Design of one parameter tuning of three-mode PID controller was developed in this present study. The integral time and the derivative time of the controller were expressed in terms of the time constant and dead time of the process. Only the proportional gain was observed to be dependent on the implemented tunable parameter in which the stable region could be predetermined by the Routh test. Extension of the concept towards designing cascade PID controllers was straightforward such that only two parameters for the inner and outer PID controllers required to be tuned, respectively. The optimal tuning correlative formulas of the proportional gain for single and cascade control systems were obtained by the least square regression method.