New results are presented concerning the state isomorphism approach to global identifiability analysis of parameterized classes of nonlinear state space systems with specified initial states. In particular we study the class of homogeneous systems, for which, under certain conditions, the local state isomorphism for a pair of indistinguishable parameter vectors is shown:to be homogeneous of degree one. For homogeneous polynomial systems, conditions are given under which the local state isomorphism becomes linear. Here, the issue of whether or not the observability rank condition holds at the origin is shown to be of key importance. The scope of the results, which extend to the multivariable case, is discussed and illustrated by a number of worked examples. This demonstrates how the developed theory can be put to use to investigate the global identifiability properties of parameterized model classes. (C) 2004 Elsevier Ltd. All rights reserved.