The growth of Ag on an ordered Al2O3 surface was studied by low energy ion scattering spectroscopy (LEIS), scanning tunneling microscopy (STM), X-ray photoelectron spectroscopy (XPS), and temperature programmed desorption (TPD). Three-dimensional (3D) growth of Ag clusters was observed with STM and LEIS, with the cluster size increasing with Ag coverage. The XPS core level binding energies and the Auger parameters indicate a weak interaction between the Ag clusters Al2O3 support. Final state effects are determined be the primary contribution to the Ag core level binding energy shift. Nonzero order kinetics was observed for Ag desorption in TPD with the Ag sublimation energy decreasing with decreasing cluster size.