화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Polymer(Korea), Vol.29, No.5, 423-432, September, 2005
Export Citation
고분자 구배표면 제조와 생체의료학적 응용
Preparation of Gradient Polymer Surface and Their Pluripotent Biomedical Applications
이해방†, 김문석, 조영호1, 강길선1, 이진호2
  • 한국화학연구원 나노생체재료연구팀
  • 1전북대학교 유기신물질공학과
  • 2한남대학교 정보신소재공학과
Hai Bang Lee†, Moon Suk Kim, Young Ho Cho1, Gilson Khang1, and Jin Ho Lee2
  • Nanobiomaterials Laboratory, Korea Research Institute of Chemical Technology, P. O. Box 107, Yuseong, Daejeon 305-343, Korea
  • 1Department of Advanced Organic Materials Engineering, Chonbuk National University, 664-14, Dukjin Ku, Jeonju 561-756, Korea
  • 2Department of Macromolecular Science, Hannam University, Korea
E-mail:
초록
지난 30년에 걸쳐 다양한 생체재료가 개발되어져 생체의료 시장에 응용되고 있다. 생물의학 분야에서 생체재료의 실질적인 활용은 생체적합성으로 언급된 생체재료에 알맞은 물리적ㆍ생물학적 반응에 대한 연구에 의존하고 있다. 다양한 표면 처리 방법을 통한 생체재료의 개질은 표면 공학 분야에서 최근에 흥미로운 주제로 떠오르고 있다. 대다수의 연구그룹들은 최근 재료의 길이에 따라 점차적으로 다양한 화학적 조성물들이 표면에 존재하게 하는 실험에 관해 초점을 모으고 있다. 이러한 "구배표면"은 생물학적 기종과 재료표면 사이의 상호작용에 대한 기초적인 응용 연구에 특별한 흥미를 보여준다. 본 총설은 한 가지 시료 위에 다양한 구배표면을 만드는 실험과 특성파악, 그리고 이들 재료표면과 생물학적 기종들과의 상호작용 규명에 초점을 두었다.
Over last three decades, various biomaterials has been developed and applied in the biomedical market. The practical utilization of biomaterials depends on the study about an appropriate physical and biological response of biomaterials. The modification of biomaterials using various surface treatment methods has recently become an interesting topic in the field of surface engineering. A gradient surface is the surface on which a gradually varying chemical composition exists along its length. A large number of research groups have been focused on the preparation of gradient surfaces. Such gradient surface is of particular interest for basic and applied studies of the interactions between biological species and surfaces since the effect of a selected property like wettability or chemical composition can be examined in a single experiment on one surface. The present review focuses on the preparation and characterization of various gradient surfaces, and their interactions with biological species.
Keywords:biomaterials;wettabiligy;hydrophilicity;hydrophobicity;biocompatibility;gradient;surface engineering;biological interaction
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