나노바이오 테크놀로지

박현규; 정봉현; Hyun Kyu Park; Bong Hyun Chung

Korean Chemical Engineering Research, Vol.44, No.1, 10-15, February, 2006

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나노바이오 테크놀로지

Nanobiotechnology

박현규, 정봉현^†

바이오나노연구센터 한국생명공학연구원, 305-333 대전시 유성구 어은동 52

Hyun Kyu Park, and Bong Hyun Chung^†

Korea Research Institute of Bioscience and Biotechnology, BioNanotechnology Research Center, 52, Oun-dong, Yuseong-gu, Daejeon 305-333, Korea

E-mail:

초록

나노바이오 테크놀로지는 최근 10년 동안 그 관심이 고조되어 왔다. 특히 의약, 약물전달 및 약리학 부분에서 분석 및 치료의 새로운 장을 여는 계기가 되었다. 나노바이오 테크놀로지는 전형적인 융합연구로서 생물학, 화학, 물리학, 공학 및 의학 연구자들의 협력을 그 기본으로 하고 있다. 본 총설에서는 나노바이오 생체분석, 나노 바이오칩/센서와 나노바이오소재를 내포하고 있는 최근 연구와 나노바이오 테크놀로지의 개발에 대한 설명 및 제시를 하고 있다.

Nanobiotechnology has attracted increasing interest during the last 10 years. Particularly in the fields of medicine, drug discovery, and pharmacology, this area of research has opened up new perspectives in analytics and therapy. Nanobiotechnolgy is a typical interdisciplinary field of research, and is based on the cooperative work of biologists, chemists, physicists, engineers, and medical doctors. This review article describes recent research and development of nanobiotechnology including nanobioanalysis, nanobiochip/sensor and nanobiomaterials.

Keywords:Nanobiotechnology;Nanobiochip;Nanobiosensor;Nanobioanalysis

[References]

Williams MC, Rouzina I, Curr. Opin. Struct. Biol., 12(3), 330 (2002)
Garini Y, Vermolen BJ, Young IT, Curr. Opin. Biotechnol., 16(1), 3 (2005)
Koopman M, Cambi A, de Bakker BI, Joosten B, Figdor CG, van Hulst NF, Garcia-Parajo MF, Febs Lett., 573(1), 6 (2004)
Biochip, Biosensor and BioMEMS technology, KRIBB BIO WATCH ISSUE (2005)
Nath N, Chilkoti A, Anal. Chem., 74(3), 504 (2002)
He L, Musick MD, Nicewarner SR, Salinas FG, Benkovic SJ, Natan MJ, Keating CD, J. Am. Chem. Soc., 122(38), 9071 (2000)
Charles Cao YW, Jin R, Mirkin CA, Science, 297(5586), 1536 (2002)
Jung JM, Shin YB, Kim MG, Ro HS, Jung HT, Chung BH, Anal. Biochem., 330(2), 251 (2004)
Ro HS, Jung SO, Kho BH, Hong HP, Lee JS, Shin YB, Kim MG, Chung BH, Appl. Environ. Microbiol., 71(2), 1089 (2005)
Kim MG, Shin YB, Jung JM, Ro HS, Chung BH, J. Immunol. Methods, 297(1-2), 125 (2005)
Jung SO, Ro HS, Kho BH, Shin YB, Kim MG, Chung BH, Proteomics, 5(17), 4427 (2005)
Kim MI, Jung SO, Park KS, Jeong EJ, Joung HA, Kim TH, Seol DW, Chung BH, Biochem. Biophys. Res. Commun., 338(4), 1834 (2005)
Cullum BM, Vo-Dinh T, Trends Biotechnol., 18(9), 388 (2000)
http://www.umich.edu/~koplab/research2/analytical/EnterPEB-BLEs. html
Clark HA, Kopelman R, Tjalkens R, Philbert MA, Anal. Chem., 71(21), 4837 (1999)
Cui Y, Zhong Z, Wang D, Wang WU, Lieber CM, Nano Lett., 3(2), 149 (2003)
Star A, Gabriel JCP, Bradley K, Gruner G, Nano Lett., 3(4), 459 (2003)
Park SJ, Taton TA, Mirkin CA, Science, 295(5559), 1503 (2002)
Haguet V, Martin D, Marcon L, Heim T, Stievenard D, Olivier C, El-Mahdi O, Melnyk O, Appl. Phys. Lett., 84(7), 1213 (2004)
Zheng G, Patolsky F, Cui Y, Wang WU, Lieber CM, Nat. Biotechnol., 23(10), 1294 (2005)
Pomerantz RT, Ramjit R, Gueroui Z, Place C, Anikin M, Leuba S, Zlatanova J, McAllister WT, Nano Lett., 5(9), 1698 (2005)
Hu Y, Das A, Hecht MH, Scoles G, Langmuir, 21(20), 9103 (2005)
He Y, Tian Y, Chen Y, Deng Z, Ribbe AE, Mao C, Angew. Chem.-Int. Ed. Engl., 44(41), 6694 (2005)

[Referenced By]

[1] Williams MC, Rouzina I, Curr. Opin. Struct. Biol., 12(3), 330 (2002)

[2] Garini Y, Vermolen BJ, Young IT, Curr. Opin. Biotechnol., 16(1), 3 (2005)

[3] Koopman M, Cambi A, de Bakker BI, Joosten B, Figdor CG, van Hulst NF, Garcia-Parajo MF, Febs Lett., 573(1), 6 (2004)

[4] Biochip, Biosensor and BioMEMS technology, KRIBB BIO WATCH ISSUE (2005)

[5] Nath N, Chilkoti A, Anal. Chem., 74(3), 504 (2002)

[6] He L, Musick MD, Nicewarner SR, Salinas FG, Benkovic SJ, Natan MJ, Keating CD, J. Am. Chem. Soc., 122(38), 9071 (2000)

[7] Charles Cao YW, Jin R, Mirkin CA, Science, 297(5586), 1536 (2002)

[8] Jung JM, Shin YB, Kim MG, Ro HS, Jung HT, Chung BH, Anal. Biochem., 330(2), 251 (2004)

[9] Ro HS, Jung SO, Kho BH, Hong HP, Lee JS, Shin YB, Kim MG, Chung BH, Appl. Environ. Microbiol., 71(2), 1089 (2005)

[10] Kim MG, Shin YB, Jung JM, Ro HS, Chung BH, J. Immunol. Methods, 297(1-2), 125 (2005)

[11] Jung SO, Ro HS, Kho BH, Shin YB, Kim MG, Chung BH, Proteomics, 5(17), 4427 (2005)

[12] Kim MI, Jung SO, Park KS, Jeong EJ, Joung HA, Kim TH, Seol DW, Chung BH, Biochem. Biophys. Res. Commun., 338(4), 1834 (2005)

[13] Cullum BM, Vo-Dinh T, Trends Biotechnol., 18(9), 388 (2000)

[14] http://www.umich.edu/~koplab/research2/analytical/EnterPEB-BLEs. html

[15] Clark HA, Kopelman R, Tjalkens R, Philbert MA, Anal. Chem., 71(21), 4837 (1999)

[16] Cui Y, Zhong Z, Wang D, Wang WU, Lieber CM, Nano Lett., 3(2), 149 (2003)

[17] Star A, Gabriel JCP, Bradley K, Gruner G, Nano Lett., 3(4), 459 (2003)

[18] Park SJ, Taton TA, Mirkin CA, Science, 295(5559), 1503 (2002)

[19] Haguet V, Martin D, Marcon L, Heim T, Stievenard D, Olivier C, El-Mahdi O, Melnyk O, Appl. Phys. Lett., 84(7), 1213 (2004)

[20] Zheng G, Patolsky F, Cui Y, Wang WU, Lieber CM, Nat. Biotechnol., 23(10), 1294 (2005)

[21] Pomerantz RT, Ramjit R, Gueroui Z, Place C, Anikin M, Leuba S, Zlatanova J, McAllister WT, Nano Lett., 5(9), 1698 (2005)

[22] Hu Y, Das A, Hecht MH, Scoles G, Langmuir, 21(20), 9103 (2005)

[23] He Y, Tian Y, Chen Y, Deng Z, Ribbe AE, Mao C, Angew. Chem.-Int. Ed. Engl., 44(41), 6694 (2005)