The activity and selectivity for partial oxidation of methanol to H-2 and CO2 on Zr, Ce, promoted Cu/Zn/Pd catalysts, have been studied using a high-throughput method of screening and analysis. In this work, infrared thermography was first used as a descriptor of overall catalytic activity. Then, activity and selectivity of samples with high infrared signal were measured in a flow reactor and characterized by BET, XRD, and XPS. Catalysts promoted with 10% Zr and showed H-2 selectivity > 95% with methanol conversion approaching 100% at similar to 200 degrees C.