Enthalpies of solution of L-threonine in aqueous solutions of isopropanol, 1,2-propanediol and propanetriol were measured and enthalpies of transfer Of L-threonine from water to these solutions calculated. Endothermic interactions, partial dehydrations and the interaction between alkyl groups, dominate exothermic interaction between polar groups. (C) 2005 Elsevier B.V. All rights reserved.