A simple synthetic method to prepare highly dispersed Pd nanoparticles in La-doped mesoporous titania with polycrystalline framework by coassembly and photoreduction is reported. The mesoporous materials were characterized by thermogravimetric (TGA)/differential scanning calorimetric (DSC), low angle and wide angle X-ray diffraction (XRD), transmission electron microscope (TEM), high-resolution transmission electron microscopy (HRTEM) and N-2 adsorption-desorption. The photocatalytic activities of the prepared mesoporous materials were evaluated by the photodegradation of methyl orange.