The potential for saving energy in the refining of cellulose-treated kraft pulp has been investigated. Kraft pulp fibers were prepared from domestic mixed-wood species of hardwood. Two kinds of commercial enzymes, consisting of cellulase and xylanase, were considered for the modification of fiber properties during pulp processing and papermaking. With the simple enzyme treatment of cellulosic fibers, some important physical factors, such as freeness development and better dewatering ability, were improved remarkably without any loss in the mechanical strength of the paper. These features consequently result in a better potentials for electric voltage saving in the refining of cellulose-treated domestic unbleached kraft pulps, presumably attributable to internal swelling of the fiber cell wall after enzymatic treatment. Therefore, in this study, basic bio-refining techniques using commercial enzymes were designed experimentally for the futures production of enzymes and papermaking mill trials.