The problem of deposition of colloidal particles onto a collector surface is investigated theoretically using Brownian dynamics simulations. Using the Kuwabara model for the flow field around the collector surface, we examine the effects of the total interaction energy profiles of the DLVO theory on the collection efficiencies. The simulation results show that: (1) the Brownian diffusion effect of particles becomes pronounced when the value of Reynolds number is close to the laminar flow region, (2) a particle size with a minimum collection efficiency exists, and (3) the dimensionless groups, N-L0, N-DL, N-E1 and N-E2 which characterize the height of the primary maximum and the depth of the secondary minimum in the total interaction energy curve play a major role in determining the collection efficiency of Brownian particles with low Reynolds numbers. In addition, we compare the present theoretical results with the;available experimental data [FitzPatrick J. A. and Spielman L. A. (1973) J. Colloid Interface Sci. 43, 350-369], and find that the simulation results obtained from the present model coincide more closely with the experimental data than those results obtained from the case where the Brownain diffusion effect is neglected.