In this study, we predict the component segmental dynamics of polyisoprene/poly(vinylethylene) (PI/PVE) blend employing a model, recently presented by Cangialosi et al. [J. Chem. Phys. 2005, 123, 144908], which combines the concept of self-concentration with the Adam-Gibbs (AG) theory of the glass transition. As the model requires the fitting of one unknown parameter connecting the characteristic length scale for segmental relaxation with the configurational entropy, PI and PVE dynamics in toluene have been investigated to extract indirectly this parameter for each of the two polymers. The employment of a mixing rule through the effective concentration to evaluate this parameter for each polymer in the blend allows the prediction of the time scale for segmental relaxation of PI and PVE in the blend. Thus, the model turns to be fully predictive. Therefore, it can be used also for those blends for which the dynamic response of the two polymers is highly overlapped as is the case of the PI/PVE blend. The characteristic length scale for segmental relaxation predicted by the model was between 1.3 and 1.8 nm for both polymers in the blend depending on the temperature.