Chloride (Cl-) salt processing in strong acids is used to recycle plutonium (Pu) from pyrochemical residues. As an alternative approach, a nitrogen dioxide (NO2) sparge is shown to effectively remove Cl- from solutions containing 6-8 M acid (H+) and up to 5 M Cl-, possibly increasing flow sheet flexibility for processing chloride-bearing pyrochemical residues. With NO2, chloride removal occurs as a result of the competition of at least two reactions, one which is acid-dependent. Below 4 M H+, NO2 reacts with Cl- to produce nitrosyl chloride (ClNO). Between 6 and 8 M H+, the reaction of hydrochloric acid (HCl) with nitric acid (HNO3), facilitated by NO2, strongly affects the Cl-removal efficiency. The effect of heating the acidic Cl- salt solution without preheating the NO2 gas has minimal effect on Cl- removal efficiency when the contact times between NO2 and the salt solution are on the order of seconds.