Individual molecular imaging with near atomic resolution has been achieved by using a spherical aberration corrected transmission electron microscope (C-s-corrected TEM). Since the spatial resolution was pushed down to 0.14 nm, enabling resolution of the typical carbon-carbon distance, we can directly assign the local configurations of hexagons and pentagons just perpendicular to the electron beam for individual fullerene molecules and identify the orientation for each C-60 molecule. The individual molecular events of fullerenes under the electron microscopic observations, such as symmetry degradation or conformation change, are demonstrated on the single-molecular basis as a consequence of the carbon atom loss. A transformation of the C-60 molecule (I-h) to C-58 (C-1), corresponding to the loss of two carbon atoms, was experimentally proposed for the first time.