The rate constants for the two channels of the reaction of F atoms with HD2 k(F) (+ HD) and k(F + DH). have been determined in, the temperature range 193-300 K. The sum of rate constants k(F+ HD) + k(F + DH) was determined by a competitive method and a discharge-flow-mass spectrometric technique, using the F + D-2 reaction as a reference reaction. By combining the results for this sum of rate constants with published results for the rate constant k(F + D2) and for the ratio of rate constants k(F + HD)/k(F + DH), values were derived for the individual rate constants k(F + HD) and k(F + DH). The experimental results are compared with published results of quantum mechanical calculations and of quasiclassical calculations on the Stark-Werner potential energy surface. (C) 2004 Elsevier B.V. All rights reserved.