Chemical Physics Letters, Vol.407, No.1-3, 58-62, 2005
Recognition of substituted cytosine derivatives by the base pairing with guanine connected to pyrene
The association constant between guanine and a series of cytosine derivatives in dichloromethane was determined by fluorescence quenching experiment of pyrene connected to guanine with methylene spacer. The association constant for guanine with 5-methyl-cytosine is found to be higher than that with cytosine. This enables us to distinguish target cytosine from its derivatives. © 2005 Elsevier B.V. All rights reserved.