Chemistry Letters, Vol.30, No.6, 546-547, 2001
Synthetic studies on lycopodium alkaloid, magellanine: Stereoselective construction of functionallized angular tricyclic skeletons by intramolecular Pauson-Khand reaction
Angular tricyclic compounds as intermediates for total synthesis of magellanine were synthesized by stereoselective Ireland-Claisen rearrangement and intramolecular Pauson-Khand reaction of exo-methylenecyclohexylalkynes. Interestingly, remarkably different reactivity was observed in the Pauson-Khand reaction of cis- and trans-disubstituted exo-methylenecyclohexylalkynes.