Chemistry Letters, Vol.31, No.2, 130-131, 2002
An efficient synthesis of the piperazinone fragment of pseudotheonamide A(1) via a stereoselective intramolecular Michael ring closure
The stereoselective intramolecular Michael ring closure of the dipeptide efficiently gives the piperazinone fragment of pseudotheonamide A(1), a serine protease inhibitor from the marine sponge Theonella swinhoei.