화학공학소재연구정보센터
Chemistry Letters, Vol.31, No.2, 140-141, 2002
Palladium-catalyzed asymmetric alkylation of 2,3-alkadienyl phosphates. Synthesis of optically active 2-(2,3-alkadienyl)malonates
Asymmetric alkylation of 2,3-alkadienyl phosphates with soft carbon nucleophiles proceeds efficiently in the presence of palladium complex catalyst bearing MeOBIPHEP or BINAP ligand to give optically active functionalized allenes up to 90% ee.