Chemistry Letters, Vol.32, No.7, 568-569, 2003
A mild, efficient and selective cleavage of aryl tert-butyldimethysilyl ethers using KOH in ethanol
An efficient and selective method for the deprotection of aryl tert-butyldimethysilyl (TBS) ethers is described. The protecting group TBS could be cleaved from aryl silyl ethers in the prensence of alkyl TBS ethers using KOH in ethanol at room temperature to give the corresponding phenols in excellent yields (87-99%).