Chemistry Letters, Vol.32, No.10, 900-901, 2003
A new method for alpha-selective glycosylation using a donor, glycosyl methyldiphenylphosphonium iodide, without any assistance of acid promoters
A mild and highly alpha-selective glycosylation of several glycosyl acceptors was performed with an in situ formed glycosyl donor, benzyl-protected glycosyl methyldiphenylphosphonium iodide, to afford the corresponding alpha-disaccharides in high yields in CH2Cl2 at room temperature without any assistance of acid promoters.