Chemistry Letters, Vol.32, No.12, 1162-1163, 2003
Highly regioselective deoxyhalogenation at the C-6 positions of N-phthaloylchitosan with N-halosuccinimide-triphenylphosphine system
N-phthaloylchitosan with high structural regularity found to be a good substrate for nucleophilic substitution with N-halosuccinimides and triphenylphosphine in N-methyl-2-pyrrolidone, which provided the corresponding 6-deoxyhalogenated derivatives in a highly regioselective manner.