화학공학소재연구정보센터
Chemistry Letters, Vol.33, No.5, 506-507, 2004
Preparative synthesis of the key intermediate, (4R,5R)-3-benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone for carbocyclic nucleosides
(4R,5R)-3-Benzyloxymethyl-4,5-isopropylidenedioxycyclopent-2-enone (1), a versatile intermediate for the synthesis of carbocyclic nucleosides was synthesized from D-ribose in 10 steps and 26% overall yield.